Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
نویسندگان
چکیده
Periconceptional intake of folic acid is known to reduce a woman's risk of having an infant affected by a neural tube birth defect (NTD). National programs to mandate fortification of food with folic acid have reduced the prevalence of NTDs worldwide. Uncertainty surrounding possible unintended consequences has led to concerns about higher folic acid intake and food fortification programs. This uncertainty emphasizes the need to continually monitor fortification programs for accurate measures of their effect and the ability to address concerns as they arise. This review highlights the history, effect, concerns, and future directions of folic acid food fortification programs.
منابع مشابه
Effect of food fortification on folic acid intake in the United States.
BACKGROUND The addition of folic acid to all enriched cereal-grain foods, mandated by the Food and Drug Administration (FDA), was initiated in January 1998. Although this program was designed such that typical folate intakes would be increased by approximately 100 micro g/d and that the risk of intakes > 1000 micro g/d (the FDA's safe upper limit of daily intake) would be minimal, its actual ef...
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Background: The addition of folic acid to all enriched cerealgrain foods, mandated by the Food and Drug Administration (FDA), was initiated in January 1998. Although this program was designed such that typical folate intakes would be increased by 100 g/d and that the risk of intakes > 1000 g/d (the FDA’s safe upper limit of daily intake) would be minimal, its actual effect on folate intake has ...
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